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CD71 Mouse anti-Human, Unlabeled, Clone: M-A712, BD

Artikelnummer. 15838248
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Mængde:
0.1 mg
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15838248 0.1 mg
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Artikelnummer. 15838248 Leverandør BD Biosciences Leverandørnr. 555534
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Forventet forsendelse: 10-08-2026
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Beskrivelse

Mouse Monoclonal Antibody

The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR). This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers. CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells. CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens. Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin. After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.

TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CD71
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon M-A712
Koncentration 0.5mg/mL
Konjugeret Unconjugated
Oversigt TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Formulering Aqueous buffered solution containing ≤0.09% sodium azide.
Værtsarter Mouse
Immunogen T-CLL and Jurkat Cells
Oprensningsmetode Affinity Purified
Mængde 0.1 mg
Regulatorisk status RUO
Forskningsdisciplin Immunology
Primær eller sekundær Primary
Målarter Human
Indhold og opbevaring Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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