anti-CD62L/L-Selectin PE-Cy7™, Clone: DREG-56, Invitrogen™

Beskrivelse

CD62L/L-Selectin Monoclonal antibody A16359 from Invitrogen specifically detects CD62L/L-Selectin in Human samples. It is validated for Flow Cytometry.

CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1, κ
Clone: DREG-56
Immunogen: Human CD62L.
Formulation: 25 Tests Purified Antibody (10mg/ml) in proprietary buffer, with 0.09% sodium azide
Synonyms: SELL, LAM-1, LAM1, LECAM1, LNHR, LSEL, LYAM1, Leu-8, Lyam-1, PLNHR, TQ1, hLHRc
Uniprot Accession: P14151
Entrez GeneID: 6402
Gene Symbol: SELL
This product detects CD62L/L-Selectin in Human samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Human CD62L.