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CD45.2 Monoclonal Antibody (104), PE-Cyanine7, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen A14736

533.36 DKK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.01000kg

Product Code. 13395574

  • 800.00 DKK / 25µg
Estimated Shipment: 19-04-2024
to see stock.

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Description

Description

CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

CD45.2 Monoclonal antibody specifically detects CD45.2 in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD45.2
Monoclonal
0.1 mg/mL
PBS with proprietary stabilizer and <0.1% sodium azide
P06800
Ptprc
B10.S mouse thymocytes and splenocytes.
25 μg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry
104
PE-Cyanine7
Ptprc
B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein
Mouse
purified
RUO
19264
4° C, store in dark, DO NOT FREEZE!
Liquid
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