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Angiotensin II human, MedChemExpress

Artikelnummer. 16445928
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Artikelnummer. 16445928 Leverandør Medchem Express Leverandørnr. HY13948

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Beskrivelse

MedChemExpress Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system.

Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

Tekniske data

Kemisk navn eller materiale Angiotensin II human
CAS 4474-91-3
Farve White
Renhedsgrad noter Research
Molekylær formel C50H71N13O12
Mængde 10 mg
Synonym Angiotensin II Ang II DRVYIHPF
Opløselighedsinformation DMSO : 100 mg/mL (95.59 mM; Need ultrasonic) ∣H2O : 50 mg/mL (47.79 mM; Need ultrasonic)
SMIL O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molekylvægt (g/mol) 1046.18
Formel vægt 1046.18
Procent renhed 98.16%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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