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Tocris Bioscience™ Angiopep-2

Artikelnummer. 30559659
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1 mg
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30559659 1 mg
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Artikelnummer. 30559659 Leverandør Tocris Bioscience™ Leverandørnr. 8828/1

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Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB

Angiopep-2 is a synthetic peptide able to specifically interact with low-density lipoprotein receptor-related protein 1 (LRP1) receptors present both on blood-brain barrier (BBB) and tumor cell membranes. Angiopep-2 binding to LRP1 facilitates receptor-mediated transcytosis of cargo across the BBB. Transcytosis-inducing molecular degraders of extracellular proteins (TransMoDEs), containing Angiopep-2 and modified to include a small-molecule ligand, induce target internalization that can cross the BBB in a variety of cell types.
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Tekniske data

CAS 906480-05-5
Mængde 1 mg
Mål LDL Receptor Peptides
Molekylær formel C104H149N29O31
Produkttype Bioactive Small Molecule
Renhed ≥95% (HPLC)
Molekylvægt (g/mol) 2301.5
Produkttitel
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