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Amiloride hydrochloride dihydrate, Thermo Scientific™

Sodium channel blocker

Brand:  Thermo Scientific Alfa Aesar J62168.06

Mængde 5g

 Se flere versioner af dette produkt

Regulatorisk: Dette produkt falder ind under Lov om kemiske stoffer og produkter - lovbekendtgørelse nr. 1755 af 22. december 2006. Hvis det er relevant, skal kunden fremskaffe en licens før levering.

Produktkode 15424599

  • 1559.72 DKK / 5g

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 μM. Amiloride • HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.

Solubility
Soluble in water at 50mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

17440-83-4
302.116
LTKVFMLMEYCWMK-UHFFFAOYSA-N
68540
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride
C6H13Cl2N7O3
MFCD00058197
amiloride hydrochloride dihydrate, modamide, nirulid, amiloride hcl, amiloride hcl dihydrate, amilorid hydrochlorid-2-wasser, unii-fzj37245uc, amiloride hydrochloride usan:usp, amiloride dihydrate hydrochloride, n-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate
CHEBI:2640
C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl

Tekniske data

Amiloride hydrochloride dihydrate
C6H13Cl2N7O3
5g
14,406
Soluble in water at 50mg/ml
C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl
302.116
CHEBI:2640
17440-83-4
MFCD00058197
UN2811
amiloride hydrochloride dihydrate, modamide, nirulid, amiloride hcl, amiloride hcl dihydrate, amilorid hydrochlorid-2-wasser, unii-fzj37245uc, amiloride hydrochloride usan:usp, amiloride dihydrate hydrochloride, n-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate
LTKVFMLMEYCWMK-UHFFFAOYSA-N
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride
68540
266.09
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