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Amikacin, MP Biomedicals™

Product Code. 17610877 Shop All MP Biomedical Products
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250 mg
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Código de producto. 17610877 Proveedor MP Biomedicals N.º de proveedor 02150342.2
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    461.00 DKK
    438.82 DKK / 250mg
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Descripción

Used to treat different types of bacterial infections. Amikacin, MP Biomedicals is an aminoglycoside antibiotic most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Ente

Amikacin works by binding to the bacterial 30S ribosomal subunit, inducing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. It interferes with the translocation of tRNA from the A-site to the P-site. Amikacin must be given by the intravenous or intramuscular route; it is not absorbed orally.

Especificaciones

Physical Form Powder
CAS 37517-28-5
pH 9.5 to 11.5 (1% aq. soln.)
Potency ca. 900μg/mg
Color White to Light Gray
Quantity 250 mg
Optical Rotation 100.5°
Molecular Formula C22H43N5O13
Boiling Point 981.8°C (760mmHg)
Synonym 1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A, O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine, Lukadin
Solubility Information Sparingly soluble in water.
InChI Key LKCWBDHBTVXHDL-RMDFUYIESA-N
SMILES C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N
IUPAC Name (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
Molecular Weight (g/mol) 585.608
PubChem CID 37768
ChEBI CHEBI:2637
Formula Weight 585.6
Grade Not Available
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