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  6. AMD 3465 hexahydrobromide, MedChemExpress

AMD 3465 hexahydrobromide, MedChemExpress

Artikelnummer. 16497016
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16497016 100 mg
16482997 50 mg
16469487 5 mg
16406948 10 mg
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Artikelnummer. 16497016 Leverandør Medchem Express Leverandørnr. HY15971

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Beskrivelse

MedChemExpress AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells

Tekniske data

Kemisk navn eller materiale AMD 3465 hexahydrobromide
Fysisk form Solid
CAS 185991-07-5
Farve Light Yellow
Mængde 100 mg
Renhedsgrad noter Research
Molekylær formel C24H44Br6N6
Til brug med (applikation) COVID-19-anti-virus
Synonym GENZ-644494 hexahydrobromide
Opløselighedsinformation DMSO : 50 mg/mL (55.80 mM; Need ultrasonic) ∣H2O : ≥ 38 mg/mL (42.41 mM)
SMIL [H]Br.[H]Br.[H]Br.[H]Br.[H]Br.[H]Br.C1(CNCC2=CC=C(CN3CCNCCCNCCNCCC3)C=C2)=NC=CC=C1
Molekylvægt (g/mol) 896.07
Formel vægt 896.07
Procent renhed 98.0%
Grad Research
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Research purposes only

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