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Alvimopan dihydrate, MedChemExpress

Artikelnummer. 16458218
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Artikelnummer. 16458218 Leverandør Medchem Express Leverandørnr. HY76657A

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Beskrivelse

MedChemExpress Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus.

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus.

Tekniske data

Kemisk navn eller materiale Alvimopan dihydrate
CAS 170098-38-1
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C25H36N2O6
Mængde 10 mg
Synonym ADL 8-2698 dihydrate LY 246736 dihydrate
Opløselighedsinformation DMSO : 33.33 mg/mL (72.37 mM; Need ultrasonic)
SMIL OC1=CC=CC([C@@]2(C)[C@@H](C)CN(C[C@H](CC3=CC=CC=C3)C(NCC(O)=O)=O)CC2)=C1.O.O
Molekylvægt (g/mol) 460.56
Formel vægt 460.56
Procent renhed 98.7%
Grad Research
Fysisk form Solid
Til brug med (applikation) Neuroscience-Neuromodulation
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Research purposes only

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