Aiolos Mouse anti-Mouse, Clone: 8B2, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-5789-82
Additional Details : Weight : 0.01000kg
DescriptionThis gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
|PBS with 0.09% sodium azide; pH 7.2|
|AIO, AIOLOS, ZNFN1A3, ikaros family zinc finger protein 3, zinc finger protein Aiolos, zinc finger protein, subfamily 1A, 3 (Aiolos)|
For Research Use Only.