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  5. Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex

Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex

Artikelnummer. 17992001
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Artikelnummer. 17992001 Leverandør Invitrogen™ Leverandørnr. QGP180ADMETOX

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Beskrivelse

De QuantiGene Plex Human ADMETOX Panel, 80-plex, muliggør måling af genekspression af al relevant ADME (absorption, distribution, metabolisme og udskillelse) og toksikologiske biomarkører gennem analyse af 80 RNA-mål i en enkelt brønd ved hjælp af Luminex xMAP teknologi i kombination med forgrenet DNA-signalamplifikation.

The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 genetic targets implicated in drug metabolism, including enzymes, transporters, and CYPs, as well as toxicology and apoptosis for efficient profiling of your drug discovery and basic research samples.

QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.

This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see create custom research panels

  • Rapid turnaround for this catalog panel for fast delivery

    • Targets: ABCA1, ABCB1 , ABCB11, ABCC1, ABCC2, ABCC3 , ABCG2 , ACTB, AOX1, B2M, BAX, BCL2, CASP3,CASP9, CES1, CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP2J2, CYP3A4, CYP3A5, CYP3A7, DPYD, FMO1, FMO3, FMO5, GAPDH, GSTA2, GSTM1, GSTP1, GSTT1, GUSB, HMGB1, HMGCS2, HNF4A, HPRT1, NAT1, NAT2, PGK1, POLR2A, PPIB, RIPK1, RXRA, SLC10A1, SLC15A1, SLC15A2, SLC16A1, SLC22A1, SLC22A2, SLC22A6, SLC22A7, SLC2A1, SLC3A1, SLCO1B1, SLCO1B3, SLCO2B1, SULT1A1, SULT2A1, SULT2B1, TBP, TFRC, TP53, TPMT, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B15, UGT2B17, UGT2B4, UGT2B7, XDH

    Panel and signal amplification technology

    QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.

    QuantiGene Plex panels contain two components: a target-specific probe set and magnetic capture beads. The target-specific probes are used to capture the RNA of interest, and branched DNA technology then amplifies the fluorescent signals, which are read with a Luminex xMAP instrument. The fluorescent signal is directly proportional to the amount of target mRNA present in the sample. This allows for (relative) quantification of gene expression and with this specific panel enables human immune profiling. Detailed and step-by-step data analysis is facilitated by the Trusted Sustainability Partner
    Suppliers who meet our established requirements for corporate social responsibility.

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    Tekniske data

    Format 96-well
    Til brug med (applikation) QuantiGene Gene Expression Assay
    Til brug med (udstyr) Luminex Instrument
    Indhold og opbevaring

    Target-specific probe set and magnetic capture beads (premixed and ready to use).

    Store probe set and capture beads at 4°C.

    Do not freeze the capture beads, as they can be damaged if frozen.
    Produktlinje QuantiGene™ Plex
    Produkttype Multiplex Panel
    Mængde 1 tallerken
    Forsendelsestilstand Wet Ice
    Prøvetype Purified RNA, cell/blood/FFPE lysates, tissue homogenates
    Detektionsmetode Fluorescence
    Forskningsområde Toxicology
    Arter Human
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    Må kun bruges til undersøgelsesformål. Må ikke anvendes ved diagnostiske procedurer.

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