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Invitrogen™ Human ACVR1 (ALK2), GST Tag Recombinant Protein

Artikelnummer. 10638703
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Mængde:
10 μg
Pakningsstørrelse:
Hver
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Artikelnummer. 10638703

Brand: Invitrogen™ PV4877

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Catalytic.

Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. ACVR1 signals a specific transcriptional response in concert with activin type II receptors. The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors. Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q04771
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 0.02% polysorbate 20, 50% glycerol, 150mM NaCl, 0.5mM EDTA, 2mM DTT and no preservative; pH 7.5
Gen-id (Entrez) 90
Molekylvægt (g/mol) 69.1 kDa
Navn Human ACVR1 (ALK2), GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias activin A receptor type 1; activin A receptor type I; activin A receptor, type 1; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor I precursor; activin receptor type I; Activin receptor type-1; activin receptor-like kinase 2; activin type I receptor; ACTRI; ActR-I; ActRIA; Acvr; ACVR1; ACVR1A; ACVRLK2; ALK2; Alk-2; ALK2-B; Alk8; ATVR1; D330013D15Rik; FOP; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; Tgfb1; Tsk7L; TSK-7L; TSRI; TSR-I; type I TGF B receptor
Fælles navn ACVR1
Gen symbol ACVR1
KinaseFamily STKR Kinase Family
Protein længde 145-509
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens 145-509
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical binding/kinetic
Kinase Group Ser⁄Thr Kinases: TKL Group
Forsendelsestilstand Dry Ice
Målindgang ACVR1
Target Gene activin A receptor, type I
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Recombinant, Catalytic
Form Liquid
Protein undertype Serine/Threonine Kinases
Forskningskategori Signal Transduction
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