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Invitrogen™ ACTH Monoclonal Antibody (AH26)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA513455
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Beskrivelse
MA5-13455 targets Adrenocorticotrophic Hormone in IHC (P) applications and shows reactivity with Human samples. The MA5-13455 immunogen is a synthetic peptide corresponding to aa 1-24 from the N-terminal of human ACTH.
ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.
Tekniske data
| ACTH | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P01189 | |
| Pomc | |
| A synthetic peptide corresponding to aa 1-24 from the N-terminal of human ACTH. | |
| 500 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin) | |
| AH26 | |
| Unconjugated | |
| Pomc | |
| ACTH; adrenal corticotropic hormone; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alphaMSH; alpha-MSH; BE; beta-endorphin; Beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; Clip; Corticotropin; Corticotropin-like intermediary peptide; corticotropin-lipotropin; Gamma-LPH; gamma-MSH; Lipotropin beta; lipotropin gamma; LPH; Melanocyte-stimulating hormone alpha; Melanocyte-stimulating hormone beta; Melanotropin alpha; melanotropin beta; Melanotropin gamma; met-enkephalin; MSH; NPP; opiomelanocortin prepropeptide; OTTHUMP00000119991; OTTHUMP00000200964; POC; Pomc; Pomc1; Pomc-1; Pomc2; Potential peptide; Precursor of MSH; pro-ACTH-endorphin; proopiomelanocortin; pro-opiomelanocortin; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); pro-opiomelanocortin-alpha; proopoimelanocortin, beta (endorphin, beta) | |
| Mouse | |
| Protein G | |
| RUO | |
| 5443 | |
| 4°C | |
| Liquid |
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