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Tocris Bioscience™ A 33
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Artikelnummer. 18796036
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Mængde:
10 mg
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18796036 10 mg
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Artikelnummer. 18796036 Leverandør Tocris Bioscience™ Leverandørnr. 6313/10

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Potent and selective PDE4B inhibitor

A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM); exhibits >100-fold selectivity for PDE4B over 4D. Regulates cAMP in inflammatory cells. Inhibits LPS-induced TNF-α production and neutrophil accumulation in mouse lungs. Reduces microglial and neutrophil activation, and improves behavioral deficits in a traumatic brain injury model in vivo. Also exhibits antidepressant-like effects. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid
CAS 915082-52-9
Mængde 10 mg
Molekylær formel C19H18ClN3O2S
Formel vægt 387.88
Produkttype Inhibitor
Renhed 98%
Produkttitel
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