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  6. A-196, MedChemExpress

A-196, MedChemExpress

Artikelnummer. 16469496
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16469496 50 mg
16445587 5 mg
16414256 100 mg
16402848 10 mg
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Artikelnummer. 16469496 Leverandør Medchem Express Leverandørnr. HY100201

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Beskrivelse

MedChemExpress A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity.

A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity.

Tekniske data

Kemisk navn eller materiale A-196
Fysisk form Solid
CAS 1982372-88-2
Farve Off-White
Mængde 50 mg
Renhedsgrad noter Research
Molekylær formel C18H16Cl2N4
Til brug med (applikation) Cancer-programmed cell death
Opløselighedsinformation DMSO : ≥ 31 mg/mL (86.29 mM)
SMIL ClC1=C(Cl)C=C(C(C2=CC=NC=C2)=NN=C3NC4CCCC4)C3=C1
Molekylvægt (g/mol) 359.25
Formel vægt 359.25
Procent renhed 99.61%
Grad Research
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Research purposes only

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