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Antibiotic A23187, 98%, Thermo Scientific™

An antibiotic and calcium ionophore

Brand:  Thermo Scientific Alfa Aesar J63020.MA

Mængde 10mg
Regulatory: A license is required to purchase this product; ROYAL ORDER OF APRIL 12, 1974.

Produktkode 15465289

  • 1701.52 DKK / 10mg

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
A23187 (Mixed Calcium-Magnesium Salt) is used in cell activation experiments when calcium dose-response data are not required. Ca-Mg ratio ∼ 1:1. it is widely used as a compound in cell activation. It is used as a highly selective Ca2+ ionophore. it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation, differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation. A23187 is a widely used ionophore. It has the ability to increase the intracellular concentrations of cations and is widely used to increase the intracellular levels of calcium. Visualization of Synaptic Ca2+ Calmodulin-Dependent Protein Kinase II Activity in Living Neurons.

Solubility
Soluble in DMSO with warming or sonication. Also soluble in ethanol or ethyl acetate

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

Antibiotic A23187
White to Yellow
C29H37N3O6
1096801
Calcimycin; Calcium ionophore A23187
HIYAVKIYRIFSCZ-CVXKHCKVSA-N
5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
97043288
98%
52665-69-7
10mg
MFCD00151202,MFCD00151202
14,1639
Soluble in DMSO with warming or sonication; Also soluble in ethanol or ethyl acetate
CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O
523.63
523.62
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