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7-Chlorokynurenic acid, MedChemExpress

Artikelnummer. 16494456
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Artikelnummer. 16494456 Leverandør Medchem Express Leverandørnr. HY100811

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Beskrivelse

MedChemExpress 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

Tekniske data

Kemisk navn eller materiale 7-Chlorokynurenic acid
CAS 18000-24-3
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C10H6ClNO3
Mængde 100 mg
Synonym 7-CKA
Opløselighedsinformation DMSO : 16.67 mg/mL (74.55 mM; Need ultrasonic) ∣H2O : 1 mg/mL (4.47 mM; Need ultrasonic)
SMIL O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O
Molekylvægt (g/mol) 223.61
Formel vægt 223.61
Procent renhed 99.13%
Grad Research
Fysisk form Solid
Til brug med (applikation) Neuroscience-Neurodegeneration
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Research purposes only

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