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Tocris Bioscience™ 5-Iodotubercidin
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Artikelnummer. 18054072
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1 mg
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18054072 1 mg
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Artikelnummer. 18054072 Leverandør Tocris Bioscience™ Leverandørnr. 1745/1

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Beskrivelse

Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases

Potent adenosine kinase inhibitor (IC50 = 26 nM). Also nucleoside transporter inhibitor (IC50 values are < 25 nM, 7 μM and 15 μM for inhibition of [3H]adenosine, [3H]uridine and [3H]formycin B uptake respectively). Strongly stimulates glycogen synthesis in hepatocytes via activation of glycogen synthase. Also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC (IC50 values are 0.4, 3.5, 5-10, 5-10, 10.9 and 27.7 μM respectively). Decreases hippocampal DNA methylation through adenosine kinase inhibition in vivo.
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Tekniske data

Kemisk navn eller materiale 5-Iodotubercidin
CAS 24386-93-4
Mængde 1 mg
Molekylær formel C11H13IN4O4
Formel vægt 392.15
Renhed 97%
Molekylvægt (g/mol) 392.15
Produkttitel
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