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  8. 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%, Thermo Scientific Chemicals

5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%, Thermo Scientific Chemicals

Catalog Number p-7042970
Click to view available options
Quantity:
50 mg
200 mg
2627-69-2
C9H14N4O5
258.23
MFCD00869751
RTRQQBHATOEIAF-UUOKFMHZSA-N
acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
17513
CHEBI:28498
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
NC(=O)C1=C(N)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
2627-69-2
C9H14N4O5
258.23
MFCD00869751
RTRQQBHATOEIAF-UUOKFMHZSA-N
acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
17513
CHEBI:28498
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
NC(=O)C1=C(N)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Description

Activator of AMP-activated protein kinase (AMPK)

5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes.

Solubility
Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY
Melting Point 214°C to 215°C
Color Brown
Quantity 50 mg
Merck Index 14,16
Solubility Information Soluble in DMSO at 2mg/ml; Soluble in water or ethanol at less than 1mg/ml
Formula Weight 258.23
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside

Safety and Handling

compliance-icons
Product Identifier
  • 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
 Supplemental information
  • MIXTURE LIST-Contains : 5-amino-1-.beta.-D-ribofuranosyl-1H-Imidazole-4-carboxamide

RUO – Research Use Only

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