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5,6-dichlorbenzimidazol ribosid, 98 %

Product Code. 15466619
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Description

CAS: 53-85-0 | C12H12Cl2N2O4 | 319,138 g/mol

Hæmmer kaseinkinase II og blokerer RNA-syntese. En adenosinanalog.5,6-dichlorbenzimidazol-ribosid anvendes som en inhibitor af RNA-polymerase II. Det er nukleosidanalog og bruges i forskning til at studere mekanismerne for cellulær regulering. Yderligere hæmmer det nogle proteinkinaser.

Denne Thermo Scientific Chemicals mærkevare var oprindeligt en del af Alfa Aesar produktportefølje. Noget dokumentation og etiketoplysninger kan referere til det gamle mærke. Originalen Alfa Aesar produkt-/varekode eller SKU-reference er ikke ændret som en del af mærkeovergangen til Thermo Scientific Chemicals .

Anvendelser
Hæmmer caseinkinase II og blokerer RNA-syntese. En adenosinanalog.5,6-dichlorbenzimidazol-ribosid anvendes som en inhibitor af RNA-polymerase II. Det er nukleosidanalog og bruges i forskning til at studere mekanismerne for cellulær regulering. Yderligere hæmmer det nogle proteinkinaser.

Opløselighed
Opløselig i DMSO til 75 mMSOpløselig i dimethylsulfoxid, varm ethanol, dimethylformamid, (1:2) dimethylformamid: Phosphatbuffer saltvand, vand, methanol og pyridin. Lidt opløselig i vandige buffere.

Bemærkninger
Inkompatibel med varme og oxidationsmidler.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 53-85-0
Molekylær formel C12H12Cl2N2O4
Molekylvægt (g/mol) 319.138
MDL nummer MFCD00036785
InChI nøgle XHSQDZXAVJRBMX-DDHJBXDOSA-N
Synonym 5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole, dichlororibofuranosylbenzimidazole, drb, 5,6-dichlorobenzimidazole riboside, 5,6-dichlorobenzimidazole 1-beta-d-ribofuranoside, 5,6-dichloro-1-.beta.-d-ribofuranosylbenzimidazole, benzimidazole, 5,6-dichloro-1-beta-d-ribofuranosyl, 5,6-dichloro-1-beta-d-ribofuranosyl-1h-benzimidazole, 2r,3r,4s,5r-2-5,6-dichloro-1,3-benzodiazol-1-yl-5-hydroxymethyl oxolane-3,4-diol, 2r,3r,4s,5r-2-5,6-dichloro-1h-1,3-benzodiazol-1-yl-5-hydroxymethyl oxolane-3,4-diol
PubChem CID 5894
IUPAC navn (2R,3R,4S,5R)-2-(5,6-dichlorbenzimidazol-1-yl)-5-(hydroxymethyl)oxolan-3,4-diol
SMIL C1=C2C(=CC(=C1Cl)Cl)N(C=N2)C3C(C(C(O3)CO)O)O

Specifications

Kemisk navn eller materiale 5,6-Dichlorobenzimidazole riboside
Farve Hvid
Mængde 50 mg
Beilstein 39123
Opløselighedsinformation Opløselig i DMSO til 75 mMSoluble i dimethylsulfoxid, varm ethanol, dimethylformamid, (1:2) dimethylformamid: Fosfatbuffersaltvand, vand, methanol og pyridin; Let opløseligt i vandige buffere.
Formel vægt 319.14
Procent renhed 98%
Fysisk form Pulver

RUO– Kun brug til forskning

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