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Thermo Scientific Chemicals 2'-Deoxyguanosine hydrate, 99%
Beskrivelse
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
Solubility
Slightly soluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Tekniske data
Specifications
| Kemisk navn eller materiale | 2'-Deoxyguanosine hydrate |
| Mængde | 100 mg |
| Beilstein | 39814 |
| Opløselighedsinformation | Slightly soluble in water. |
| Optisk rotation | −32° (c=0.5 in Water) |
| Formel vægt | 267.25 (Anhydrous) |
| Procent renhed | 99% |
Safety and Handling
- Advarsel
- Akut toksicitet Kategori 4
- H302-Farlig ved indtagelse.
- P264-Vask grundigt efter brug.
- P301+P330+P331-I TILFÆLDE AF INDTAGELSE: Skyl munden. Fremkald IKKE opkastning.
- P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .
RUO – Research Use Only
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