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Thermo Scientific Chemicals 2'-Deoxyguanosine hydrate, 99%

Artikelnummer. 11343566
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Mængde:
100 mg
500 mg
Pakningsstørrelse:
100mg
500mg
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Artikelnummer. 11343566

Brand: Thermo Scientific Chemicals L14519.MC

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Beskrivelse

CAS: 961-07-9 | C10H13N5O4 | 267.25 g/mol

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Solubility
Slightly soluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 961-07-9
Molekylær formel C10H13N5O4
Molekylvægt (g/mol) 267.25
MDL nummer MFCD00150760
InChI nøgle YKBGVTZYEHREMT-DWFKHXNSNA-N
Synonym 2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl
PubChem CID 187790
ChEBI CHEBI:17172
IUPAC navn 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
SMIL NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Tekniske data

Kemisk navn eller materiale 2'-Deoxyguanosine hydrate
Mængde 100 mg
Beilstein 39814
Opløselighedsinformation Slightly soluble in water.
Optisk rotation −32° (c=0.5 in Water)
Formel vægt 267.25 (Anhydrous)
Procent renhed 99%

Sikkerhed og håndtering

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  • P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .

RUO – Research Use Only

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