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R&D Systems™ 2-APB

Artikelnummer. 18075342
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18075342 10 mg
18034702 50 mg
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Artikelnummer. 18075342 Leverandør R&D Systems™ Leverandørnr. 1224/10
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Beskrivelse

A Tocris product, part of R&D Systems. IP3 receptor antagonist. Also TRP channel modulator

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 524-95-8
Molekylær formel C14H16BNO

Tekniske data

Kemisk navn eller materiale 2-APB
Mængde 10 mg
Produktlinje Tocris
Formel vægt 225.1
Renhed >98%
Molekylvægt (g/mol) 225.10
Produkttitel
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