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Gibco™ PeproGMP® Human IL-3 Recombinant Protein, PeproTech®

Artikelnummer. 30275259
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Mængde:
1 mg
100 μg
50 μg
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Artikelnummer. 30275259

Brand: Gibco™ GMP20003100UG

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Beskrivelse

Recombinant Protein

Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P08700
Til brug med (applikation) Control, Western Blot Control, Bioactivity
Format Lyophilized
Formulering Protein with no preservative
Gen-id (Entrez) 3562
Molekylvægt (g/mol) 15 kDa
Navn PeproGMP™ Human IL-3
Oprensningsmetode Purified
Mængde 100 μg
Opbevaringskrav -20°C or -80°C if preferred
Regulatorisk status GMP
Endotoksin koncentration ≤0.1 EU/μg
Gene Alias BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Fælles navn IL-3
Gen symbol IL3
Biologisk aktivitet Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 ha been tested against the WHO standard NIBSC 91/510.
Produkttype Protein
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Indhold og opbevaring -20°Cor to +80°C if preferred
Aktivitet Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 has been tested against the WHO standard NIBSC 91/510. Find the International Unit (IU) value <a href='https://www.thermofisher.com/us/en/home/life-science/cell-culture/cell-culture-learning-center/recombinant-protein-information/international-units.html'>here</a>.
Udtrykssystem E. coli
Form Lyophilized
Produktlinje PeproGMP
Renhed eller kvalitetsklasse ≥ 98% by SDS-PAGE gel and HPLC analyses.
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