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1,1-Dimethylbiguanide hydrochloride, Thermo Scientific™

1,1-Dimethylbiguanide hydrochloride (metformin hydrochloride, CAS # 115-70-4) is the salt of methylated biguanide, a compound exhibiting anti-hyperglycemic properties.

321.65 DKK - 2552.28 DKK

Kemiske identifikatorer

CAS 1115-70-4
Molekylær formel C4H12ClN5
Molekylvægt (g/mol) 165.63
MDL nummer MFCD00012582
InChI nøgle OETHQSJEHLVLGH-UHFFFAOYSA-N
Synonym metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
PubChem CID 14219
IUPAC navn hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
SMIL [H+].[Cl-].CN(C)C(=N)N=C(N)N
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Thermo Scientific Alfa Aesar
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Descripción

Descripción

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1

• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes

• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells

• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway

• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders

• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell

Especificaciones

Identificadores de productos químicos

1115-70-4
165.63
OETHQSJEHLVLGH-UHFFFAOYSA-N
14219
[H+].[Cl-].CN(C)C(=N)N=C(N)N
C4H12ClN5
MFCD00012582
metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride

Especificaciones

1,1-Dimethylbiguanide hydrochloride
C4H12ClN5
MFCD00012582
metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
OETHQSJEHLVLGH-UHFFFAOYSA-N
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
14219
1115-70-4
NH2C(=NH)NHC(=NH)N(CH3)2·HCl
14,5938
Soluble in water (50mg/ml),ethanol,and DMSO (50 mM).
[H+].[Cl-].CN(C)C(=N)N=C(N)N
165.63
165.62
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Seguridad y manipulación

Seguridad y manipulación

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

missing translation for 'einecsNumber' : 214-230-6

missing translation for 'rtecsNumber' : DU1800000

missing translation for 'tsca' : No

Recommended Storage : Keep cold

SDS
Documentos

Documentos

Product Certifications

RUO – Research Use Only

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