Solvents, Blends, reagents and additives that meet the stringent purity requirements of LC-MS
Solvents, Blends, Reagents and Additives that meet the stringent purity requirements of LC-MS
The certified performance of our Optima LC-MS products offers the most reliable solutions for today’s scientist. For consistent, reproducible performance in the mobile phase of LC-MS, choose Optima LC-MS grade products:
- Solvents
- Mobile Phase Blends
- Reagents & Additives

Fisher Chemical Optima LC-MS solvents have set the standard of excellence for consistent, reproducible performance in the mobile phase of LC-MS.
Key Features
- Higher signal intensity & lower metal ion content (up to 17 metals level tested)
- Innovative LC-UV Gradient test with Photo Diode Array detector
- Sub-micron filtration for maximum purity
Advantages
- Ensure extremely low levels of UV-absorbing impurities – Peak Height with PDA (from 200 to 400 nm) with 2mAU max
- Range of pack sizes available to suit application requirements
- Lower particulate levels < 0.1μ filtration to protect columns and components from clogging

Blends that meet the stringent purity requirements of LC-MS
Fisher Chemical Optima LC-MS solvents have set the standard of excellence for consistent, reproducible performance in the mobile phase of LC-MS. Now these same high purity solvents are pre-blended with Optima LC-MS modifiers, such as formic acid (FA) or trifluoroacetic acid (TFA), to provide ready to use aqueous and organic mobile phase blends for LC-MS applications.
Key Features
- Low mass spectrometry background noise (LC-MS)
- Minimal metal impurities
- Lowest impurity background using diode array reduction (LC-UV)
Advantages
- Safety risks associated with storing, blending and disposing of hazardous solvents
- Overhead costs associated with preparing blends
- Eliminates the need to clean glassware or measure corrosive acids
- Extend LC-MS column life due to low impurity level and low residue value

Reagents and additives that meet the stringent purity requirements of LC-MS
Optima LC-MS grade reagents are used as ultra-pure additives in the formulation of solvent blends for the mobile phase of LC-MS applications. Our mobile phase additives are use-tested to ensure suitability and are also protease-free.
Key Features
- Low spectrometry background noise
- Minimal metal impurities
- Lowest impurity background using diode array detection (LC-UV)
Advantages
- Available in ampules for small volumes and HDPE bottles for larger quantities
- Convenient, ready to use ampules for easy dilution
- Ampules are pre-scored for easy opening – no need to fi ll the ampules