CAS RN 944328-88-5
IUPAC Navn:
2-{[9-({[1,1'-biphenyl]-4-yl}methyl)-2-(2,3-dihydro-1H-inden-5-yloxy)-9H-purin-6-yl]amino}-3-phenylpropan-1-ol
Synonymer:
2-[(9-{[1,1'-biphenyl]-4-ylmethyl}-2-(2,3-dihydro-1H-inden-5-yloxy)purin-6-yl)amino]-3-phenylpropan-1-ol
Molekylvægt (g/mol):
567.69
Molekylformel:
C36H33N5O2
InChi Key:
DOKZLKDGUQWMSX-UHFFFAOYNA-N
SMILES:
OCC(CC1=CC=CC=C1)NC1=C2N=CN(CC3=CC=C(C=C3)C3=CC=CC=C3)C2=NC(OC2=CC3=C(CCC3)C=C2)=N1
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Resultater
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Tocris Bioscience™ QS 11
CAS: 944328-88-5 Molekylær formel: C36H33N5O2
2
QS11, MedChemExpress
MedChemExpress QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 modulates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells.
