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H3CNNOHNCH3CH3HONNONNH2

CAS RN 937174-76-0

IUPAC Navn: 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(piperidin-3-yl)methoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Synonymer: 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Molekylvægt (g/mol): 425.49
Molekylformel: C21H27N7O3
InChi Key: KGPGFQWBCSZGEL-UHFFFAOYNA-N
SMILES: CCN1C(=NC2=C(N=CC(OCC3CCCNC3)=C12)C#CC(C)(C)O)C1=NON=C1N
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1 – 2 af 2 Resultater
1

Tocris Bioscience™ GSK 690693
GREENER_CHOICE

2

GSK-690693, MedChemExpress

MedChemExpress GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale GSK-690693
Sundhedsfare 1 H301
Formel vægt 425.48
Opløselighedsinformation DMSO : 30 mg/mL (70.51 mM; Need ultrasonic) ∣H2O : 5 mg/mL (11.75 mM; ultrasonic and adjust pH to 5 with HCl)
Procent renhed 96.35%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 425.48
CAS 937174-76-0
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL CC(O)(C)C#CC1=NC=C(OC[C@@H]2CNCCC2)C3=C1N=C(C4=NON=C4N)N3CC
Renhedsgrad noter Research
Molekylær formel C21H27N7O3
Til brug med (applikation) Cancer-Kinase/protease