CAS RN 879085-55-9

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1 – 3 af 3 Resultater

1

Novus Biologicals™ Vismodegib Hedgehog inhibitor

May be dissolved in DMSO (200 mg/mL); or ethanol (10 mg/mL, warm)

Pris og tilgængelighed
Tekniske data

CAS	879085-55-9
Indhold og opbevaring	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Donorkilde	Synthetic

2

Tocris Bioscience™ Vismodegib

Potent hedgehog pathway inhibitor

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Anbefalet opbevaring	Store at -20°C
CAS	879085-55-9
Mål	Hedgehog Signaling Inhibitors
Renhed	0.98
Molekylær formel	C₁₉H₁₄Cl₂N₂O₃S

3

Vismodegib, MedChemExpress

MedChemExpress Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.

ENCOMPASS_PREFERRED

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Vismodegib
Sundhedsfare 1	H361
Formel vægt	421.3
Opløselighedsinformation	DMSO : 50 mg/mL (118.68 mM; Need ultrasonic) ∣Ethanol : 3.33 mg/mL (7.90 mM; ultrasonic and warming and heat to 60°C)
Procent renhed	95.75%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	421.3
CAS	879085-55-9
Synonym	GDC-0449
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₁₄Cl₂N₂O₃S
Til brug med (applikation)	Cancer-programmed cell death