CAS RN 863971-12-4

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MedChemExpress MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	MMAF-OMe
Formel vægt	745.99
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (134.05 mM)
Procent renhed	96.68%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molekylvægt (g/mol)	745.99
CAS	863971-12-4
Synonym	Monomethyl auristatin F methyl ester
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
SMIL	CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(OC)=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
Renhedsgrad noter	Research
Molekylær formel	C₄₀H₆₇N₅O₈
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 863971-12-4

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