CAS RN 854001-07-3

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Dasatinib hydrochloride, MedChemExpress

MedChemExpress Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of apoptosis and autophagy.

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Tekniske data

Kemisk navn eller materiale	Dasatinib hydrochloride
Formel vægt	524.47
Opløselighedsinformation	DMSO : 15 mg/mL (28.60 mM; Need ultrasonic and warming) ∣H2O : 10 mg/mL (19.07 mM; Need ultrasonic)
Procent renhed	98.01%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	524.47
CAS	854001-07-3
Synonym	BMS-354825 hydrochloride
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₂₂H₂₇Cl₂N₇O₂S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 854001-07-3

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