CAS RN 780757-88-2

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Tocris Bioscience™ ICG 001

Inhibits TCF/β-catenin-mediated transcription

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Tekniske data

Kemisk navn eller materiale	(6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
Anbefalet opbevaring	Store at -20°C
CAS	780757-88-2
Mål	beta-Catenin Inhibitors
Renhed	0.98
Molekylær formel	C₃₃H₃₂N₄O₄

MedChemExpress ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	ICG-001
Formel vægt	548.63
Opløselighedsinformation	DMSO : ≥ 50 mg/mL (91.14 mM)
Procent renhed	98.3%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	548.63
CAS	780757-88-2
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NCC1=CC=CC=C1)N2CCC(N([C@@]2(CN(C3=O)CC4=C5C=CC=CC5=CC=C4)[H])[C@H]3CC6=CC=C(C=C6)O)=O
Renhedsgrad noter	Research
Molekylær formel	C₃₃H₃₂N₄O₄
Til brug med (applikation)	Cancer-programmed cell death

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