CAS RN 646502-53-6

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VcMMAE, MedChemExpress

MedChemExpress VcMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	VcMMAE
Sundhedsfare 1	H302
Formel vægt	1316.63
Opløselighedsinformation	DMSO : ≥ 54 mg/mL (41.01 mM)
Procent renhed	97.09%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	-20°C, sealed storage, away from moisture and light∣The compound is unstable in solutions, freshly prepared is recommended.
Molekylvægt (g/mol)	1316.63
CAS	646502-53-6
Synonym	MC-Val-Cit-PAB-MMAE mc-vc-PAB-MMAE
Holdbarhed	-20°C, sealed storage, away from moisture and light∣The compound is unstable in solutions, freshly prepared is recommended.
SMIL	CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(CCCCCN4C(C=CC4=O)=O)=O
Renhedsgrad noter	Research
Molekylær formel	C₆₈H₁₀₅N₁₁O₁₅

CAS RN 646502-53-6

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