CAS RN 475488-23-4

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NVP-ADW742, MedChemExpress

MedChemExpress NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	NVP-ADW742
Formel vægt	453.58
Opløselighedsinformation	DMSO : 19.23 mg/mL (42.40 mM; Need ultrasonic)
Procent renhed	98.31%
Fysisk form	Powder
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	453.58
CAS	475488-23-4
Synonym	ADW742 GSK 552602A ADW
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	NC1=C2C(N(C=C2C3=CC=CC(OCC4=CC=CC=C4)=C3)[C@H]5C[C@@H](C5)CN6CCCC6)=NC=N1
Renhedsgrad noter	Research
Molekylær formel	C₂₈H₃₁N₅O
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 475488-23-4

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