CAS RN 2444764-03-6

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MedChemExpress GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 μM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 μM, but only weakly affected PKA.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	GKI-1
Formel vægt	269.73
Opløselighedsinformation	DMSO : 200 mg/mL (741.48 mM; Need ultrasonic)
Procent renhed	98.02%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	269.73
CAS	2444764-03-6
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	ClC(C=C1)=CC=C1NC2=CC(C3=CNN=C3)=CC=C2
Renhedsgrad noter	Research
Molekylær formel	C₁₅H₁₂ClN₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 2444764-03-6

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