CAS RN 229005-80-5
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Tocris Bioscience™ TAK 779
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
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TAK-779, MedChemExpress
MedChemExpress TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.