CAS RN 2098836-45-2

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Tocris Bioscience™ AT 1

(+)-JQ1 based PROTAC with selectivity for BRD4

Pris og tilgængelighed

BRD4 degrader AT1, MedChemExpress

MedChemExpress BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	BRD4 degrader AT1
Formel vægt	972.68
Opløselighedsinformation	DMSO : 100 mg/mL (102.81 mM; Need ultrasonic)
Procent renhed	98.69%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	972.68
CAS	2098836-45-2
Holdbarhed	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(NCCCCCCSC(C)(C)[C@H](NC(C)=O)C(N4[C@@H](C[C@@H](O)C4)C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)=O)C7=NN=C(C)N27
Renhedsgrad noter	Research
Molekylær formel	C₄₈H₅₈ClN₉O₅S₃
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 2098836-45-2

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Tocris Bioscience™ AT 1