CAS RN 1950634-92-0

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Tocris Bioscience™ dBET6

Potent and selective (+)-JQ1 based Degrader (PROTAC™) targeting BET bromodomains, active in vivo

Pris og tilgængelighed

dBET6, MedChemExpress

MedChemExpress dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	dBET6
Formel vægt	841.37
Opløselighedsinformation	DMSO : 50 mg/mL (59.43 mM; Need ultrasonic)
Procent renhed	98.12%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	841.37
CAS	1950634-92-0
Holdbarhed	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Renhedsgrad noter	Research
Molekylær formel	C₄₂H₄₅ClN₈O₇S
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1950634-92-0

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Tocris Bioscience™ dBET6 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ dBET6