CAS RN 1948273-02-6

IUPAC Navn: —

Synonymer: —

Molekylvægt (g/mol): —

Molekylformel: —

InChi Key: —

SMILES: —

Snævre resultater

1 – 1 af 1 Resultater

(S,R,S)-AHPC-Me, MedChemExpress

MedChemExpress (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	(S,R,S)-AHPC-Me
Formel vægt	444.59
Opløselighedsinformation	DMSO : 250 mg/mL (562.32 mM; Need ultrasonic)
Procent renhed	97.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	444.59
CAS	1948273-02-6
Synonym	VHL ligand 2 E3 ligase Ligand 1A
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₃H₃₂N₄O₃S
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1948273-02-6

Filtrerede søgeresultater

Snævre resultater