CAS RN 1652591-81-5

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GSK484 hydrochloride, MedChemExpress

MedChemExpress GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	GSK484 hydrochloride
Formel vægt	510.03
Opløselighedsinformation	DMSO : 125 mg/mL (245.08 mM; Need ultrasonic) ∣H2O : 50 mg/mL (98.03 mM; Need ultrasonic)
Procent renhed	97.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	510.03
CAS	1652591-81-5
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	O=C(N1C[C@H](N)[C@H](O)CC1)C2=CC(OC)=C3C(N=C(C(N4CC5CC5)=CC6=C4C=CC=C6)N3C)=C2.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₂₇H₃₂ClN₅O₃
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1652591-81-5

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