CAS RN 133407-82-6
CAS RN 133407-82-6
IUPAC Navn:
benzyl N-{3-methyl-1-[(3-methyl-1-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}butyl)carbamoyl]butyl}carbamate
Synonymer:
benzyl N-{3-methyl-1-[(3-methyl-1-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}butyl)carbamoyl]butyl}carbamate
Molekylvægt (g/mol):
475.63
Molekylformel:
C26H41N3O5
InChi Key:
TZYWCYJVHRLUCT-UVKLAMSESA-N
SMILES:
CC(C)C[C@H](NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
1
–
4
af
4
Resultater
1
2
Tocris Bioscience™ MG 132
Proteasome and calpain inhibitor. Inhibits NF-κB activation
3
STEMCELL Technologies (S)-MG132
Ubiquitin-proteasome and NF-κB pathway inhibitor; Inhibits proteasome and stabilizes IκB
4
MG-132, MedChemExpress
MedChemExpress MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis.