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Aromatiske organiske heterocykliske forbindelser, der består af en femleddet ring med fire carbonatomer og et nitrogenatom, der danner en aminfunktionel gruppe.

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1

AZ PFKFB3 26, MedChemExpress

MedChemExpress AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale AZ PFKFB3 26
Formel vægt 402.49
Opløselighedsinformation DMSO : 5 mg/mL (12.42 mM; ultrasonic and adjust pH to 3 with HCl)
Procent renhed 98.38%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 402.49
CAS 1704740-52-2
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C([C@H]1NCCC1)NC2=CC=C(OC3=CC4=C(N(CC(C)C)C=C4C#N)C=C3)C=C2
Renhedsgrad noter Research
Molekylær formel C24H26N4O2
Til brug med (applikation) Cancer-Kinase/protease
2

Trilaciclib hydrochloride, MedChemExpress

MedChemExpress Trilaciclib hydrochloride (G1T28 hydrochloride) is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Trilaciclib hydrochloride
Formel vægt 519.47
Opløselighedsinformation H2O : 25.64 mg/mL (49.36 mM; ultrasonic and adjust pH to 2 with HCl) ∣DMSO : 1.1 mg/mL (2.12 mM; Need ultrasonic)
Procent renhed 98.2%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol) 519.47
CAS 1977495-97-8
Synonym G1T28 hydrochloride
Holdbarhed 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL O=C1C2=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C=N4)N=C3N2C6(CCCCC6)CN1.[H]Cl.[H]Cl
Renhedsgrad noter Research
Molekylær formel C24H32Cl2N8O
Til brug med (applikation) Cancer-Kinase/protease
3

Indoximod, MedChemExpress

MedChemExpress Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer.

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