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Akrylsyrer og derivater

Organiske forbindelser, der består af en carboxylsyre med en vinylfunktionel gruppesubstitution; vinyl funktionelle grupper er en carbon-carbon dobbeltbinding. Omfatter forbindelser, der er afledt af akrylsyrer.

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1

Salvianolic acid B, MedChemExpress

MedChemExpress Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Salvianolic acid B
Formel vægt 718.61
Opløselighedsinformation H2O : 50 mg/mL (69.58 mM; ultrasonic and adjust pH to 3 with HCl) ∣DMSO : 25 mg/mL (34.79 mM; Need ultrasonic)
Procent renhed 98.07%
Fysisk form Solid
Farve Light Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molekylvægt (g/mol) 718.61
CAS 121521-90-2
Synonym Lithospermic acid B
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
SMIL O=C([C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC4=CC=C(O)C(O)=C4)=O)=C13)O[C@@H](C(O)=O)CC5=CC=C(O)C(O)=C5
Renhedsgrad noter Research
Molekylær formel C36H30O16
Til brug med (applikation) COVID-19-immunoregulation
2

100MG Piroctone olamine

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3

Enoxacin hydrate, MedChemExpress

MedChemExpress Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 μg/ml) and topoisomerase IV (IC50=26.5 μg/ml).

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Kemisk navn eller materiale Enoxacin hydrate
Formel vægt 347.34
Opløselighedsinformation 1M NaOH : 100 mg/mL (287.90 mM; ultrasonic and adjust pH to 11 with NaOH) ∣DMSO : 2.78 mg/mL (8.00 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.88 mM; ultrasonic and warming and heat to 80°C)
Procent renhed 98.15%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molekylvægt (g/mol) 347.34
CAS 84294-96-2
Synonym Enoxacin sesquihydrateAT-2266 hydrateCI-919 hydrate
Holdbarhed 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
SMIL O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=N2)C1=O)O.[1.5H2O]
Renhedsgrad noter Research
Molekylær formel C15H17FN4O3.3/2H2O
Til brug med (applikation) COVID-19-immunoregulation
4

Gilteritinib hemifumarate, MedChemExpress

MedChemExpress Gilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.

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Kemisk navn eller materiale Gilteritinib hemifumarate
Formel vægt 610.75
Opløselighedsinformation H2O : 2 mg/mL (3.27 mM; Need ultrasonic) ∣Ethanol : 2 mg/mL (3.27 mM; ultrasonic and warming and adjust pH to 3 with 1M HCl and heat to 60°C) ∣DMSO : 1.74 mg/mL (2.85 mM; Need ultrasonic and warming)
Procent renhed 98.34%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol) 610.75
CAS 1254053-84-3
Synonym ASP2215 hemifumarate
Holdbarhed 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL OC(/C=C/C(O)=O)=O.NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O.[0.5]
Renhedsgrad noter Research
Molekylær formel C29H44N8O3 0.5C4H4O4
Til brug med (applikation) Cancer-Kinase/protease
5

Dicoumarol, MedChemExpress

MedChemExpress Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively.

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