Små molekyler omfattende to mononukleotider, adenosinmonophosphat (AMP) og nikotinamidmononukleotid (NMN); oxiderede og reducerede nikotinamidadenindinukleotider i deres uphosphorylerede (NAD+ eller NADH) og phosphorylerede (NADP+ eller NADPH) former.
MedChemExpress Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
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