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Pyridin nukleotider

Små molekyler omfattende to mononukleotider, adenosinmonophosphat (AMP) og nikotinamidmononukleotid (NMN); oxiderede og reducerede nikotinamidadenindinukleotider i deres uphosphorylerede (NAD+ eller NADH) og phosphorylerede (NADP+ eller NADPH) former.

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1

Nicotinamide riboside chloride, MedChemExpress

MedChemExpress Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.

ENCOMPASS_PREFERRED
2

NAD+, MedChemExpress

MedChemExpress NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale NAD+
Sundhedsfare 1 H303∣H371
Formel vægt 663.43
Opløselighedsinformation H2O : 41.67 mg/mL (62.81 mM; Need ultrasonic)
Procent renhed 98.24%
Fysisk form Powder
Farve White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 663.43
CAS 53-84-9
Synonym β-DPN β-NAD β-Nicotinamide Adenine Dinucleotide
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O[C@H]([C@@H]1O)[C@@H](O[C@@H]1COP(OP(OC[C@H]2O[C@@H]([N+]3=CC=CC(C(N)=O)=C3)[C@H](O)[C@@H]2O)([O-])=O)(O)=O)N4C(N=CN=C5N)=C5N=C4
Renhedsgrad noter Research
Molekylær formel C21H27N7O14P2
Til brug med (applikation) Metabolism-protein/nucleotide metabolism