The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; FLB6421 ZAP ZC3H2 ZC3HAV1 ZC3HDC2 Zinc finger antiviral protein; Inactive Poly [ADP-ribose] polymerase 13; PARP13; ZAP; Zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; Zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type, antiviral 1
Cat # 16868265
150 µL
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150 µL
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100 µL
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100 µL
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20 µL
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100 µg
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100 uL
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100 µL
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100 µL
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100 ug
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