Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Fliz1 ZC3HDC8 zinc finger CCCH domain-containing protein 8 zinc finger CCCH type domain containing 8 zinc finger CCCH-type domain containing 8; Zinc finger CCCH domain-containing protein 8; zinc finger CCCH type domain containing 8; zinc finger CCCH-type domain containing 8
Cat # 15906564
100 µL
Cat # 15774961
100 µL
Cat # 15784961
100 µL
Cat # 15674095
100 µL
Cat # 15912055
100 µL
Cat # 16165470
100 uL
Cat # 16834685
150 µL
Cat # 16668434
100 µL
Cat # 13299828
100 µL
Cat # 16844685
20 µL
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