The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
(E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; E2(17)KB 2; p53-regulated ubiquitin-conjugating enzyme 1; ubc2e ubiquitin conjugating enzyme; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin conjugating enzyme E2D 2; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2 D2 Ubiquitin carrier protein D2 Ubiquitin-conjugating enzyme E2(17)KB 2 Ubiquitin-conjugating enzyme E2-17 kDa 2 Ubiquitin-protein ligase D2 p53-regulated ubiquitin-conjugating enzyme 1 PUBC1 UBC4 UBC5B UBCH4 UBCH5B; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase D2
Cat # 16363605
100 µL
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100 µL
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100 µL
Cat # 16167195
100 µg
Cat # 16643205
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Cat # 15986394
100 µL
Cat # 15555362
100 µL
Cat # 15932105
100 µL
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