UBA6 (UBE1L2, MOP-4) is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family. It is a part of the cascade to attach ubiquitin (Ub) covalently to substrate proteins. UBA6 activates ubiquitin by first adenylating its carboxy-terminal glycine residue with ATP and then linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Its isoforms influence spermatogenesis and male fertility. UBA6 is highly expressed in human monocytes.
E1-L2; E1-L2 MOP-4 UBE1L2 UBA6 ubiquitin-activating enzyme E1 monocyte protein 4 ubiquitin-activating enzyme 6 ubiquitin-activating enzyme E1-like 2 ubiquitin-activating enzyme E1-like protein 2 ubiquitin-like modifier-activating enzyme 6; Monocyte protein 4; MOP-4; UBA6, ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme 6; ubiquitin-activating enzyme E1-like 2; Ubiquitin-activating enzyme E1-like protein 2; ubiquitin-like modifier activating enzyme 6; Ubiquitin-like modifier-activating enzyme 6
Cat # 13247138
100 µg
Cat # 16569541
100 µL
Cat # 13405177
100 µL
Cat # 15735801
100 µL
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