RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3′-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3′-splice site.
Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1-like 3; U2 small nuclear RNA auxiliary factor 1-like 4; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like 3; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2AF1-like 4; U2AF1-like protein 3; U2AF1L3V1 U2AF1L3 U2 small nuclear RNA auxiliary factor 1-like 4 U2AF1RS3 U2af26 U2AF1-RS3
Cat # 15939114
100 µL
Cat # 16166969
50 µg
Cat # 15527471
100 µL
Cat # 16029446
100 ug
Cat # 11346803
100 µg
Cat # 17141544
100 µL
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