Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
1700020J09Rik AU023439 CAG repeat protein 32 CAGH32 Domino homolog E1A-binding protein p400 Ep400 hDomino KIAA1498 KIAA1818 mDomino mKIAA1498 P400 p400 kDa SWI2/SNF2-related protein TNRC12 Trinucleotide repeat-containing gene 12 protein; CAG repeat protein 32; Domino homolog; E1A-binding protein p400; hDomino; p400 kDa SWI2/SNF2-related protein; p400 SWI2/SNF2-related protein; trinucleotide repeat containing 12; Trinucleotide repeat-containing gene 12 protein
Cat # 17177613
100 µL
Cat # 16350895
100 µL
Cat # 13435287
100 µL
Cat # 15761411
100 µL
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